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Monday, May 4, 2020 | History

3 edition of Bioassay of sulfisoxazole for possible carcinogenicity. found in the catalog.

Bioassay of sulfisoxazole for possible carcinogenicity.

National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

Bioassay of sulfisoxazole for possible carcinogenicity.

by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

  • 196 Want to read
  • 38 Currently reading

Published by Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program in Bethesda, Md .
Written in English

    Subjects:
  • Carcinogens.,
  • Anti-infective agents -- Toxicology.

  • Edition Notes

    SeriesCarcinogenesis technical report series ; no. 138, DHEW publication ; no. (NIH) 79-1393, DHEW publication -- no. (NIH) 79-1393.
    The Physical Object
    Paginationxii, 118 p. :
    Number of Pages118
    ID Numbers
    Open LibraryOL15225987M

    FUNDAMENTAL AND APPLIED TOXICOLOGY () Issues The Redundancy of Mouse Carcinogenicity Bioassays MANFRED SCHACH yon WITTENAU and PAUL C. ESTES Department of Drug Safety Evaluation, Pfizer Central Research, Groton, CT ABSTRACT The Redundancy of Mouse Carcinogenicity by:   Gantrisin (acetyl sulfisoxazole pediatric suspension) (sulfisoxazole) is an antibacterial sulfonamide available as a pediatric suspension for oral administration. Each teaspoonful (5 mL) of the pediatric suspension contains the equivalent of approximately gm sulfisoxazole in the form of acetyl sulfisoxazole in a vehicle containing %.

    Medscape - Indication-specific dosing for Pediazole (erythromycin base, sulfisoxazole), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Notice: Except where noted, spectra from this collection were measured on dispersive instruments, often in carefully selected solvents, and hence may differ in detail from measurements on FTIR instruments or in other chemical environments. More information on the manner in which spectra in this collection were collected can be found here. Notice: .

    Find patient medical information for Sulfisoxazole Acetyl Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Preparing Stock Solutions. The following data is based on the product molecular weight Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock ry: ETA Receptors.


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Bioassay of sulfisoxazole for possible carcinogenicity by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. Download PDF EPUB FB2

Bioassay of sulfisoxazole for possible carcinogenicity (OCoLC) Material Type: Government publication, National government publication: Document Type: Book: All Authors Bioassay of sulfisoxazole for possible carcinogenicity.

book Contributors: National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. OCLC Number: Notes: "CAS no. " Description. Online book: Additional Physical Format: Print version: National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

Bioassay of sulfisoxazole for possible carcinogenicity (OCoLC) Material Type: Document, Government publication, National government publication, Internet resource: Document Type: Internet Resource, Computer File.

BIOASSAY OF SULFISOXAZOLE FOR POSSIBLE CARCINOGENICITY. Carcinogenesis Testing Program. Division of Cancer Caus ane d Prevention National Cancer Institute National Institute osf Health Bethesda, Maryland U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE Public Health Service National Institute osf Health.

DREW Publication No. |a Bioassay of sulfisoxazole for possible carcinogenicity |h [electronic resource] / |c Carcinogenesis Testing Program, Division of Cancer Cause and Prevention, National Cancer Institute, National Institutes of Health. A bioassay of sulfisoxazole for possible carcinogenicity was conducted by admin the chemical by gavage to Fischer rats and B6C3Fl mice.

Groups of 50 rats of each sex and 50 mice of each sex were admin sulfisoxazole suspended in aqueous % carboxymethyl cellulose 7 days/wk at one of two doses, either or mg/kg body weight for the. Ivett, J.L., Brown, B.M., Rodgers, C., Anderson, B.E., Resnick, M.A., Zeiger, E.

Chromosomal aberration and sister chromatid exchange tests in Chinese hamster ovary. Bioassay of ICRF for possible carcinogenicity Published: () Bioassay of sulfisoxazole for possible carcinogenicity Published: () Bioassay of estradiol mustard for possible carcinogenicity Published: ().

Sulfisoxazole should not be given to infants younger than 2 months of age unless directed by your child's doctor. Sulfisoxazole may cause serious unwanted effects in this age group. Take sulfisoxazole with a full glass (8 ounces) of water.

Several additional glasses of water should be taken during the day, unless otherwise directed by your doctor. A bioassay for possible carcinogenicity of sulfallat wae s con­ ducted using Osborne-Mendel rat ands B6C3F1 mice.

Sulfallat was e administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animal os f each species. Twent anyd 5 mic0 e rats of each sex were placed on test as controls for the bioassay. Bioassay of Sulfisoxazole for Possible Carcinogenicity (CAS No.

The role of transgenic mouse models in carcinogen identification. (Research) Detection of drug-dependent antibodies by the 51Cr platelet lysis test: documentation of immune thrombocytopenia induced by.

Applies to sulfisoxazole: compounding powder, oral suspension, oral tablet. General. In general, although not every side effect listed in the side effects section may have been reported with the use of sulfisoxazole, they have all been reported with the use of one or more sulfonamide compounds.

Sulfisoxazole was generally well tolerated. Author(s): Hazleton Laboratories America.; Carcinogenesis Testing Program (U.S.); National Institutes of Health (U.S.) Title(s): Bioassay of sulfisoxazole for. Bioassay of sulfallate for possible carcinogenicity (CAS No.

National Toxicology Program. A bioassay for possible carcinogenicity of sulfallate was conducted using Osborne-Mendel rats and B6C3F1 mice.

Sulfallate was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species. Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an dimethyl-isoxazole substituent. It has antibiotic activity against a wide range of Gram-negative and Gram-positive organisms.

It is sometimes given in combination with erythromycin Excretion: Excreted unchanged in urine. sulfisoxazole >98 Section 4 - FIRST AID MEASURES SWALLOWED If swallowed do NOT induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration.

Observe the patient Size: KB. sulfisoxazole: [ sul″fĭ-sok´sah-zōl ] a short-acting sulfonamide antibacterial; used as the base or as sulfisoxazole acetyl particularly for infections of the urinary tract and as sulfisoxazole diolamine as a topical ophthalmic antibacterial.

A bioassay of chlorpropamide for possible carcinogenicity was conducted by administering the test material in feed to Fischer rats and B6C3F1 mice. Groups of 35 rats and 35 mice of each sex were administered chlorpropamide as follows: rats 5 days/wk for to wk at 3, or 6, ppm, and mice 5 days wk for 34 wk at 5, or 10, ppm.

Start studying Sulfisoxazole. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Erythromycin and sulfisoxazole is an antibiotic that fights bacteria.

Sulfisoxazole is a sulfa drug that also fights bacteria in the body. Erythromycin and sulfisoxazole is a combination medicine. IUPAC Standard InChIKey: NHUHCSRWZMLRLA-UHFFFAOYSA-N CAS Registry Number: Chemical structure: This structure is also available as a 2d Mol file or as a.

The pharmacokinetics of sulfisoxazole was studied in 6 elderly (age years) and 7 young (age years) healthy nonsmoking volunteers following the oral administration of 2 g of Gantrisin.

The plasma levels of sulfisoxazole obtained in the postabsorption phase were higher in the elderly subjects.Chemoprophylaxis of Recurrences of Rheumatic Fever DRUG DOSE Benzathine penicillin G 1, units every 4 weeks Penicillin V mg twice a day OR Sulfadiazine or g once a day for patients Sulfisoxazole [is less than or equal to] 27 kg (60 lbs) g once a day for patients > 27 kg (60 lbs) For Individuals allergic to penicillin and.Sulfisoxazole, a sulfonamide, is an antibacterial agent that acts by inhibiting the folic acid metabolism.

1 It is also a non-selective endothelin antagonist. It is effective in the treatment of recurrent acute otitis media and also in rendering protection .